Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin

Author(s)
Vladimir Chobot, Franz Hadacek, Gert Bachmann, Wolfram Weckwerth, Lenka Kubicova
Abstract

The flavanol (±)-catechin shows an OH group but no 4-keto group on ring C (C3), and no conjugation between ring A and B. The related flavanone (+)-eriodictyol has a keto group on C4 but no 3-OH group on ring C. (+)-Taxifolin, another flavanone, has an OH on C3 and a keto group on C4 of the C ring. Deoxyribose degradation assay systems, with hydrogen peroxide and ascorbic acid either added or omitted, were performed in variants in which Fe(III) was added in a complex with ethylenediaminetetraacetic acid (EDTA). In combination with differential pulse voltammetry (DVP), the specific redox-chemical contributions of the ring A m-dihydroxyl groups could be explored more specifically in addition to those of the traditionally investigated o-dihydroxyl groups of ring B.

Organisation(s)
Department of Ecogenomics and Systems Biology, Research Platform Vienna Metabolomics Center
Journal
International Journal of Molecular Sciences
Volume
17
ISSN
1661-6596
DOI
https://doi.org/10.3390/ijms17121986
Publication date
11-2016
Publication status
Published
Peer reviewed
Yes
Austrian Fields of Science 2012
104013 Natural product chemistry, 104005 Electrochemistry, 106034 Phytochemistry, 303009 Nutritional sciences
Keywords
flavonoids, Fenton reaction, deoxyribose degradation assay, differential pulse voltammetry, redox chemistry
Portal url
https://ucris.univie.ac.at/portal/en/publications/pro-and-antioxidant-activity-of-three-selected-flavan-type-flavonoids-catechin-eriodictyol-and-taxifolin(403e05fd-745d-42e7-bbe7-3a18ebd18950).html