Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin

Author(s)
Vladimir Chobot, Franz Hadacek, Gert Bachmann, Wolfram Weckwerth, Lenka Kubicova
Abstract

The flavanol (±)-catechin shows an OH group but no 4-keto group on ring C (C3), and no conjugation between ring A and B. The related flavanone (+)-eriodictyol has a keto group on C4 but no 3-OH group on ring C. (+)-Taxifolin, another flavanone, has an OH on C3 and a keto group on C4 of the C ring. Deoxyribose degradation assay systems, with hydrogen peroxide and ascorbic acid either added or omitted, were performed in variants in which Fe(III) was added in a complex with ethylenediaminetetraacetic acid (EDTA). In combination with differential pulse voltammetry (DVP), the specific redox-chemical contributions of the ring A m-dihydroxyl groups could be explored more specifically in addition to those of the traditionally investigated o-dihydroxyl groups of ring B.

Organisation(s)
Department of Ecogenomics and Systems Biology, Research Platform Vienna Metabolomics Center
External organisation(s)
Georg-August-Universität Göttingen
Journal
International Journal of Molecular Sciences
Volume
17
ISSN
1661-6596
DOI
https://doi.org/10.3390/ijms17121986
Publication date
11-2016
Peer reviewed
Yes
Austrian Fields of Science 2012
Natural product chemistry, Electrochemistry, Phytochemistry, Nutritional sciences
Keywords
Portal url
https://ucris.univie.ac.at/portal/en/publications/pro-and-antioxidant-activity-of-three-selected-flavan-type-flavonoids-catechin-eriodictyol-and-taxifolin(403e05fd-745d-42e7-bbe7-3a18ebd18950).html