Poly(ADP-Ribose)Polymerase Activity Controls Plant Growth by Promoting Leaf Cell Number
- Author(s)
- Philipp Schulz, Karel Jansseune, Thomas Degenkolbe, Michael Meret, Hannes Claeys, Aleksandra Skirycz, Markus Teige, Lothar Willmitzer, Matthew A. Hannah
- Abstract
A changing global environment, rising population and increasing demand for biofuels are challenging agriculture and creating a need for technologies to increase biomass production. Here we demonstrate that the inhibition of poly (ADPribose) polymerase activity is a promising technology to achieve this under non-stress conditions. Furthermore, we investigate the basis of this growth enhancement via leaf series and kinematic cell analysis as well as single leaf transcriptomics and plant metabolomics under non-stress conditions. These data indicate a regulatory function of PARP within cell growth and potentially development. PARP inhibition enhances growth of Arabidopsis thaliana by enhancing the cell number. Time course single leaf transcriptomics shows that PARP inhibition regulates a small subset of genes which are related to growth promotion, cell cycle and the control of metabolism. This is supported by metabolite analysis showing overall changes in primary and particularly secondary metabolism. Taken together the results indicate a versatile function of PARP beyond its previously reported roles in controlling plant stress tolerance and thus can be a useful target for enhancing biomass production.
- Organisation(s)
- Department of Biochemistry and Cell Biology
- External organisation(s)
- Chinese Academy of Sciences (CAS), Bayer Cropscience, Universität Wien, Ghent University , Vlaams Instituut voor Biotechnologie
- Journal
- PLoS ONE
- Volume
- 9
- No. of pages
- 15
- ISSN
- 1932-6203
- DOI
- https://doi.org/10.1371/journal.pone.0090322
- Publication date
- 02-2014
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 106008 Botany
- Keywords
- ASJC Scopus subject areas
- Agricultural and Biological Sciences(all), General, Biochemistry, Genetics and Molecular Biology(all)
- Portal url
- https://ucris.univie.ac.at/portal/en/publications/polyadpribosepolymerase-activity-controls-plant-growth-by-promoting-leaf-cell-number(921edc08-2dc6-4b17-9fe0-fc65e787638f).html