Detecting horizontal gene transfer among microbiota
- Author(s)
- Jana Schwarzerova, Michal Zeman, Vladimir Babak, Katerina Jureckova, Marketa Nykrynova, Margaret Varga, Wolfram Weckwerth, Monika Dolejska, Valentine Provaznik, Ivan Rychlik, Darina Cejkova
- Abstract
Horizontal gene transfer (HGT) is a key driver in the evolution of bacterial genomes. The acquisition of genes mediated by HGT may enable bacteria to adapt to ever-changing environmental conditions. Long-term application of antibiotics in intensive agriculture is associated with the dissemination of antibiotic resistance genes among bacteria with the consequences causing public health concern. Commensal farm-animal-associated gut microbiota are considered the reservoir of the resistance genes. Therefore, in this study, we identified known and not-yet characterized mobilized genes originating from chicken and porcine fecal samples using our innovative pipeline followed by network analysis to provide appropriate visualization to support proper interpretation.
- Organisation(s)
- Functional and Evolutionary Ecology, Research Platform Vienna Metabolomics Center
- External organisation(s)
- Brno University of Technology, Veterinary Research Institute, University of Oxford, University of Veterinary Sciences Brno, Department of Clinical Microbiology and Immunology, Institute of Laboratory Medicine, The University Hospital Brno , Brno, Czech Republic., Charles University Prague, Masaryk University, Universität Wien
- Journal
- Microbiology Spectrum
- Volume
- 12
- Pages
- e0196423
- ISSN
- 2165-0497
- DOI
- https://doi.org/10.1128/spectrum.01964-23
- Publication date
- 01-2024
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 106023 Molecular biology, 106014 Genomics
- Keywords
- ASJC Scopus subject areas
- Microbiology (medical), Infectious Diseases, Genetics, Immunology and Microbiology(all), Physiology, Cell Biology, Ecology
- Sustainable Development Goals
- SDG 3 - Good Health and Well-being
- Portal url
- https://ucris.univie.ac.at/portal/en/publications/detecting-horizontal-gene-transfer-among-microbiota(1e517e4a-5ddd-438f-8f91-2320cac169d5).html