New Publication in Journal of Hazardous Materials


Ferroptosis is the key cellular process mediating Bisphenol A responses in Chlamydomonas and a promising target for enhancing microalgae-based bioremediation

The recent research was published by Palak Chaturvedi, Arindam Ghatak and Wolfram Weckwerth in collaboration with the University of Oviedo, Asturias, Spain. It highlights the physiological and proteomic response of Chlamydomonas reinhardtii during long-term BPA exposure. BPA imbalanced iron and redox homeostasis, disrupting cell function and triggering FERROPTOSIS. In this work, we addressed the molecular mechanisms involved in BPA exposure, demonstrating for the first time the induction of ferroptosis in eukaryotic algae and how ROS detoxification mechanisms and other specific proteomic rearrangements reverted this situation.

Read the full text here: