Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation
- Author(s)
- Jayne Louise Wilson, Thomas Naegele, Monika Linke, Florian Demel, Stephanie D. Fritsch, Hannah Katharina Mayr, Zhengnan Cai, Karl Katholnig, Xiaoliang Sun, Lena Fragner, Anne Miller, Arvand Haschemi, Alexandra Popa, Andreas Bergthaler, Markus Hengstschlaeger, Thomas Weichhart, Wolfram Weckwerth
- Organisation(s)
- Research Platform Vienna Metabolomics Center, Functional and Evolutionary Ecology
- External organisation(s)
- Medizinische Universität Wien, Österreichische Akademie der Wissenschaften (ÖAW), Ludwig-Maximilians-Universität München, Universität Wien
- Journal
- Cell Reports
- Volume
- 30
- Pages
- 1542-1552
- ISSN
- 2211-1247
- DOI
- https://doi.org/10.1016/j.celrep.2020.01.011
- Publication date
- 02-2020
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 106002 Biochemistry, 101028 Mathematical modelling, 106052 Cell biology, 106044 Systems biology
- Keywords
- ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Portal url
- https://ucris.univie.ac.at/portal/en/publications/inverse-datadriven-modeling-and-multiomics-analysis-reveals-phgdh-as-a-metabolic-checkpoint-of-macrophage-polarization-and-proliferation(8453632d-b7f0-43fe-8994-c44a676803b5).html