Systematic Comparison of Advanced Network Analysis and Visualization of Lipidomics Data
- Author(s)
- Jana Schwarzerová, Dominika Olešová, Aleš Kvasnička, David Friedecký, Margaret Varga, Valentine Provazník, Wolfram Weckwerth
- Abstract
Comprehensive analysis of lipids is becoming a forefront of clinical data analysis. Due to significant technical advancements, lipidomics is emerging in clinical diagnostics for improvement and earlier detection of a broad range of diseases. However, in order to understand the biological complexities and interrelationships between the molecules, it is important to have a correct representation of the data and visualizations that enable good interpretability of the lipidomic data. Therefore, the present study systematically compares different visualization methods for lipidomic data, based on different computational relations between the selected lipids and supplemented with known biological information. Networks were reconstructed, and an analysis was performed to objectively compare the visualizations.
- Organisation(s)
- Functional and Evolutionary Ecology
- External organisation(s)
- Brno University of Technology, University of Vienna, Slovak Academy of Sciences (SAS), Palacký University Olomouc, University of Oxford
- Pages
- 378-389
- No. of pages
- 12
- DOI
- https://doi.org/10.1007/978-3-031-34953-9_30
- Publication date
- 06-2023
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 301302 Lipidomics research, 106005 Bioinformatics
- Keywords
- ASJC Scopus subject areas
- Theoretical Computer Science, General Computer Science
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/37887f7d-a926-40b9-802a-d2f00a910c93