Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

Author(s)
Mohamed Elgendy, Marco Cirò, Amir Hosseini, Jakob Weiszmann, Luca Mazzarella, Elisa Ferrari, Riccardo Cazzoli, Giuseppe Curigliano, Andrea DeCensi, Bernardo Bonanni, Alfredo Budillon, Pier Giuseppe Pelicci, Veerle Janssens, Manfred Ogris, Manuela Baccarini, Luisa Lanfrancone, Wolfram Weckwerth, Marco Foiani, Saverio Minucci
Organisation(s)
Research Platform Vienna Metabolomics Center, Department of Microbiology, Immunobiology and Genetics
External organisation(s)
European Institute of Oncology, IFOM-FIRC Institute of Molecular Oncology, Ospedali Galliera, Istituto Nazionale Tumori, IRCCS-Fondazione G. Pascale, Katholieke Universiteit Leuven, Università degli Studi di Milano-Bicocca
Journal
Cancer Cell
Volume
35
Pages
798-815.e5
No. of pages
23
ISSN
1535-6108
DOI
https://doi.org/10.1016/j.ccell.2019.03.007
Publication date
2019
Peer reviewed
Yes
Austrian Fields of Science 2012
301206 Pharmacology
Keywords
ASJC Scopus subject areas
Oncology, Cancer Research, Cell Biology
Portal url
https://ucrisportal.univie.ac.at/en/publications/fdcd3686-5fe2-4e82-8618-a2643bb78a76